Plasma phospholipid omega-3 fatty acids and incidence of postoperative atrial fibrillation in the OPERA trial.
Identifieur interne : 000554 ( Main/Exploration ); précédent : 000553; suivant : 000555Plasma phospholipid omega-3 fatty acids and incidence of postoperative atrial fibrillation in the OPERA trial.
Auteurs : Jason H Y. Wu [États-Unis] ; Roberto Marchioli ; Maria G. Silletta ; Alejandro Macchia ; Xiaoling Song ; David S. Siscovick ; William S. Harris ; Serge Masson ; Roberto Latini ; Christine Albert ; Nancy J. Brown ; Mauro Lamarra ; Roberto R. Favaloro ; Dariush MozaffarianSource :
- Journal of the American Heart Association ; 2013.
English descriptors
- KwdEn :
- Aged, Atrial Fibrillation (blood), Atrial Fibrillation (epidemiology), Cardiac Surgical Procedures, Dietary Supplements, Docosahexaenoic Acids (blood), Eicosapentaenoic Acid (blood), Fatty Acids, Unsaturated (blood), Female, Fish Oils (administration & dosage), Humans, Incidence, Male, Middle Aged, Postoperative Complications (blood), Postoperative Complications (epidemiology), Prospective Studies.
- MESH :
- chemical , administration & dosage : Fish Oils.
- chemical , blood : Docosahexaenoic Acids, Eicosapentaenoic Acid, Fatty Acids, Unsaturated.
- blood : Atrial Fibrillation, Postoperative Complications.
- epidemiology : Atrial Fibrillation, Postoperative Complications.
- Aged, Cardiac Surgical Procedures, Dietary Supplements, Female, Humans, Incidence, Male, Middle Aged, Prospective Studies.
Abstract
Long-chain polyunsaturated omega-3 fatty acids (n-3 PUFA) demonstrated antiarrhythmic potential in experimental studies. In a large multinational randomized trial (OPERA), perioperative fish oil supplementation did not reduce the risk of postoperative atrial fibrillation (PoAF) in cardiac surgery patients. However, whether presupplementation habitual plasma phospholipid n-3 PUFA, or achieved or change in n-3 PUFA level postsupplementation are associated with lower risk of PoAF is unknown.
DOI: 10.1161/JAHA.113.000397
PubMed: 24145742
Affiliations:
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Le document en format XML
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Silletta</name></author><author><name sortKey="Macchia, Alejandro" sort="Macchia, Alejandro" uniqKey="Macchia A" first="Alejandro" last="Macchia">Alejandro Macchia</name></author><author><name sortKey="Song, Xiaoling" sort="Song, Xiaoling" uniqKey="Song X" first="Xiaoling" last="Song">Xiaoling Song</name></author><author><name sortKey="Siscovick, David S" sort="Siscovick, David S" uniqKey="Siscovick D" first="David S" last="Siscovick">David S. Siscovick</name></author><author><name sortKey="Harris, William S" sort="Harris, William S" uniqKey="Harris W" first="William S" last="Harris">William S. 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Wu</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Epidemiology, Harvard School of Public Health, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Marchioli, Roberto" sort="Marchioli, Roberto" uniqKey="Marchioli R" first="Roberto" last="Marchioli">Roberto Marchioli</name></author><author><name sortKey="Silletta, Maria G" sort="Silletta, Maria G" uniqKey="Silletta M" first="Maria G" last="Silletta">Maria G. Silletta</name></author><author><name sortKey="Macchia, Alejandro" sort="Macchia, Alejandro" uniqKey="Macchia A" first="Alejandro" last="Macchia">Alejandro Macchia</name></author><author><name sortKey="Song, Xiaoling" sort="Song, Xiaoling" uniqKey="Song X" first="Xiaoling" last="Song">Xiaoling Song</name></author><author><name sortKey="Siscovick, David S" sort="Siscovick, David S" uniqKey="Siscovick D" first="David S" last="Siscovick">David S. Siscovick</name></author><author><name sortKey="Harris, William S" sort="Harris, William S" uniqKey="Harris W" first="William S" last="Harris">William S. Harris</name></author><author><name sortKey="Masson, Serge" sort="Masson, Serge" uniqKey="Masson S" first="Serge" last="Masson">Serge Masson</name></author><author><name sortKey="Latini, Roberto" sort="Latini, Roberto" uniqKey="Latini R" first="Roberto" last="Latini">Roberto Latini</name></author><author><name sortKey="Albert, Christine" sort="Albert, Christine" uniqKey="Albert C" first="Christine" last="Albert">Christine Albert</name></author><author><name sortKey="Brown, Nancy J" sort="Brown, Nancy J" uniqKey="Brown N" first="Nancy J" last="Brown">Nancy J. Brown</name></author><author><name sortKey="Lamarra, Mauro" sort="Lamarra, Mauro" uniqKey="Lamarra M" first="Mauro" last="Lamarra">Mauro Lamarra</name></author><author><name sortKey="Favaloro, Roberto R" sort="Favaloro, Roberto R" uniqKey="Favaloro R" first="Roberto R" last="Favaloro">Roberto R. Favaloro</name></author><author><name sortKey="Mozaffarian, Dariush" sort="Mozaffarian, Dariush" uniqKey="Mozaffarian D" first="Dariush" last="Mozaffarian">Dariush Mozaffarian</name></author></analytic><series><title level="j">Journal of the American Heart Association</title><idno type="e-ISSN">2047-9980</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Atrial Fibrillation (blood)</term><term>Atrial Fibrillation (epidemiology)</term><term>Cardiac Surgical Procedures</term><term>Dietary Supplements</term><term>Docosahexaenoic Acids (blood)</term><term>Eicosapentaenoic Acid (blood)</term><term>Fatty Acids, Unsaturated (blood)</term><term>Female</term><term>Fish Oils (administration & dosage)</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Middle Aged</term><term>Postoperative Complications (blood)</term><term>Postoperative Complications (epidemiology)</term><term>Prospective Studies</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Fish Oils</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Docosahexaenoic Acids</term><term>Eicosapentaenoic Acid</term><term>Fatty Acids, Unsaturated</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Atrial Fibrillation</term><term>Postoperative Complications</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Atrial Fibrillation</term><term>Postoperative Complications</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Cardiac Surgical Procedures</term><term>Dietary Supplements</term><term>Female</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Long-chain polyunsaturated omega-3 fatty acids (n-3 PUFA) demonstrated antiarrhythmic potential in experimental studies. In a large multinational randomized trial (OPERA), perioperative fish oil supplementation did not reduce the risk of postoperative atrial fibrillation (PoAF) in cardiac surgery patients. However, whether presupplementation habitual plasma phospholipid n-3 PUFA, or achieved or change in n-3 PUFA level postsupplementation are associated with lower risk of PoAF is unknown.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Massachusetts</li></region></list><tree><noCountry><name sortKey="Albert, Christine" sort="Albert, Christine" uniqKey="Albert C" first="Christine" last="Albert">Christine Albert</name><name sortKey="Brown, Nancy J" sort="Brown, Nancy J" uniqKey="Brown N" first="Nancy J" last="Brown">Nancy J. Brown</name><name sortKey="Favaloro, Roberto R" sort="Favaloro, Roberto R" uniqKey="Favaloro R" first="Roberto R" last="Favaloro">Roberto R. Favaloro</name><name sortKey="Harris, William S" sort="Harris, William S" uniqKey="Harris W" first="William S" last="Harris">William S. Harris</name><name sortKey="Lamarra, Mauro" sort="Lamarra, Mauro" uniqKey="Lamarra M" first="Mauro" last="Lamarra">Mauro Lamarra</name><name sortKey="Latini, Roberto" sort="Latini, Roberto" uniqKey="Latini R" first="Roberto" last="Latini">Roberto Latini</name><name sortKey="Macchia, Alejandro" sort="Macchia, Alejandro" uniqKey="Macchia A" first="Alejandro" last="Macchia">Alejandro Macchia</name><name sortKey="Marchioli, Roberto" sort="Marchioli, Roberto" uniqKey="Marchioli R" first="Roberto" last="Marchioli">Roberto Marchioli</name><name sortKey="Masson, Serge" sort="Masson, Serge" uniqKey="Masson S" first="Serge" last="Masson">Serge Masson</name><name sortKey="Mozaffarian, Dariush" sort="Mozaffarian, Dariush" uniqKey="Mozaffarian D" first="Dariush" last="Mozaffarian">Dariush Mozaffarian</name><name sortKey="Silletta, Maria G" sort="Silletta, Maria G" uniqKey="Silletta M" first="Maria G" last="Silletta">Maria G. Silletta</name><name sortKey="Siscovick, David S" sort="Siscovick, David S" uniqKey="Siscovick D" first="David S" last="Siscovick">David S. Siscovick</name><name sortKey="Song, Xiaoling" sort="Song, Xiaoling" uniqKey="Song X" first="Xiaoling" last="Song">Xiaoling Song</name></noCountry><country name="États-Unis"><region name="Massachusetts"><name sortKey="Wu, Jason H Y" sort="Wu, Jason H Y" uniqKey="Wu J" first="Jason H Y" last="Wu">Jason H Y. Wu</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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